Liquid biopsy research

A clearer view between clinical evaluations.

We are exploring CTC enrichment and imaging as a longitudinal research signal—designed to complement established cancer care.

Conceptual sequence of circulating tumour cell observations changing over time
Serial CTC observation conceptIllustrative—not clinical evidence
Our focus

After diagnosis: monitoring treatment response research—not population screening.

Conceptual illustration of circulating tumour cells being separated from other cells in a blood sample
Liquid biopsy and CTC enrichment conceptIllustrative

What is a liquid biopsy?

A repeatable window into cancer biology.

A liquid biopsy examines blood or another body fluid for cancer-related material. It may look for tumour DNA, RNA, proteins or whole circulating tumour cells. Our work focuses on CTCs: rare cancer cells that have entered the bloodstream.

01

Simple sampling

A blood sample can be collected at planned clinical visits.

02

Repeat over time

Baseline and follow-up samples can be compared during treatment.

03

Cell-level information

CTCs can be counted and imaged to study changes in intact tumour-derived cells.

Liquid biopsy does not replace tissue biopsy, imaging, pathology or a clinician’s assessment.

Why follow CTCs?

The trend may be more useful than one measurement.

A single result is a snapshot. Repeated CTC measurements may help researchers observe whether the cell count or cell features change during treatment, then compare that trend with scans, pathology, blood markers and clinical findings.

01

Establish a baseline

Measure CTCs before or at the start of treatment to create a reference point.

02

Observe the direction

Follow whether CTC numbers or visible features rise, fall or remain stable.

03

Compare the evidence

Study whether the CTC trend agrees with imaging, tumour markers and the patient’s clinical course.

Longitudinal study concept

Designed around change, not a single result.

01

Baseline

Establish a pretreatment research reference.

02

Follow-up

Collect at protocol-defined treatment stages.

03

Process

Enrich rare cells with a consistent workflow.

04

Observe

Enumerate and image candidate CTCs.

05

Correlate

Relate trends to standard clinical data.

A complementary signal

One more piece of the cancer picture.

No single test explains the whole disease. CTC information may add a cell-based view alongside established evidence, helping researchers build a more complete longitudinal picture.

Established information

What it commonly shows

What CTC research may add

Imaging

Where a tumour is and how its size changes.

A blood-based cell trend between scheduled scans.

Tissue pathology

Cancer type, grade and important tissue features.

Intact tumour-derived cells that can be counted and imaged repeatedly.

Blood tumour markers

Levels of selected proteins or other molecules.

A cell-based signal that may change differently from soluble markers.

Clinical assessment

Symptoms, examination findings and overall response.

An additional research measure to correlate with the patient’s course.

Important: CTC results should be interpreted together with validated tests and clinical findings. MIOPC™ is under development for research use and is not a standalone diagnostic test.

Personalised monitoring research

Study the trajectory, not just the snapshot.

Serial cell-level observations could help researchers investigate why patients with similar diagnoses may follow different treatment trajectories.

Our objective is to support research into more informed, patient-specific monitoring—not to automate treatment recommendations.

What the references suggest

CTCs can add complementary information.

Together, these references suggest that CTCs may provide important complementary information for patient treatment monitoring. CTC findings are most useful when interpreted alongside imaging, pathology, validated tumour markers and clinical assessment.

Planning a longitudinal CTC study?

Share the cancer context, sampling schedule and research endpoint. We can explore technical fit together.

Discuss a study